Deciphering the microbiology of respiratory infection using precision metagenomics analysis

Carpenter, R. E., Sadia, A., Brown, E., Vine, T., Sharma, R.
Publication date
November 2022
Association for Molecular Pathology (AMP) 2022 Annual Meeting & Exposition
Phoenix, AZ
Pulmonary infections are the major cause of morbidity and mortality worldwide. Co-infection of bacteria, fungi, viruses, and parasites is common in Pulmonary infections. Rapid and accurate pathogen identification enables targeted therapy. Metagenomic Next generation sequencing (mNGS) is a powerful emerging tool in clinical diagnosis to overcome the limitations of routine microbiological and PCR methods. Precision Metagenomics uses a targeted sequencing of clinically relevant targets using the hybridization capture-based targeted regions. The approach may improve diagnostic accuracy for guiding antibiotic prescriptions.
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